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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
26.06
Human Site:
T458
Identified Species:
47.78
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
T458
Q
I
L
P
K
H
K
T
N
E
K
Q
E
K
S
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
T472
Q
I
L
P
K
H
K
T
N
E
K
Q
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
T458
Q
I
L
P
K
H
K
T
N
E
K
Q
E
K
S
Dog
Lupus familis
XP_537704
2182
240593
T467
Q
V
L
P
K
H
K
T
N
E
K
Q
E
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
T458
Q
V
L
P
K
H
K
T
N
E
K
Q
D
K
S
Rat
Rattus norvegicus
NP_001100505
2040
223488
S363
G
M
D
T
D
S
A
S
Q
R
L
V
I
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
T454
P
V
A
A
K
H
K
T
N
E
K
Q
E
K
G
Chicken
Gallus gallus
XP_415884
2225
244861
T502
Q
A
A
P
K
H
K
T
N
E
K
Q
D
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
E404
S
N
G
V
C
E
E
E
T
D
K
A
S
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
P529
D
E
N
E
Q
N
K
P
P
Q
D
S
K
Q
L
Honey Bee
Apis mellifera
XP_393643
1982
216109
M305
C
Y
V
L
V
T
D
M
D
D
S
P
P
D
T
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
F590
R
I
Q
K
K
F
D
F
H
A
Y
H
K
K
H
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
66.6
73.3
N.A.
6.6
N.A.
6.6
0
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
73.3
80
N.A.
20
N.A.
40
26.6
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
0
0
8
0
0
8
0
8
0
0
8
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
16
0
8
16
8
0
16
8
0
% D
% Glu:
0
8
0
8
0
8
8
8
0
54
0
0
39
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
54
0
0
8
0
0
8
0
0
8
% H
% Ile:
0
31
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
62
0
62
0
0
0
62
0
16
62
0
% K
% Leu:
0
0
39
8
0
0
0
0
0
0
8
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
8
0
0
54
0
0
0
0
0
0
% N
% Pro:
8
0
0
47
0
0
0
8
8
0
0
8
8
0
0
% P
% Gln:
47
0
8
0
8
0
0
0
8
8
0
54
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
8
0
0
8
8
8
8
39
% S
% Thr:
0
0
0
8
0
8
0
54
8
0
0
0
0
0
8
% T
% Val:
0
24
8
8
8
0
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _